Mappa interattiva delle epidemie

Sudan virus disease outbreak declared by Uganda MOH on 30 January 2025. Affected seven districts: Fort Portal City, Jinja, Kampala, Kyegegwa, Mbale, Ntoroko, Wakiso. Emergency vaccine trial (TOKOMEZA SVD) launched 4 days after declaration. Outbreak declared over 26 April 2025 after 42 consecutive days with no new cases. WHO deployed 67 experts; US$3.4M released from Contingency Fund for Emergencies.

WHO Disease Outbreak News (1 December 2025) reported a new cluster of Ebola virus disease in North Kivu. Rapidly contained through ring vaccination. Marked DRC's 16th declared Ebola event.

WHO Disease Outbreak News (5 September 2025) reported an Ebola virus disease cluster in South Kivu. Ring vaccination and contact tracing contained the outbreak within 67 days.

Brief outbreak in South Kivu rapidly contained through ring vaccination and contact tracing within 45 days.

The first confirmed Ebola outbreak in Equatorial Guinea. Index case in Kie-Ntem Province, later spreading to Litoral Province. Notable 80% CFR. Cross-border alert issued for Cameroon and Gabon. WHO and Africa CDC coordinated response.

First confirmed Ebola outbreak in Tanzania, caused by Sudan ebolavirus. All cases epidemiologically linked in Kagera Region near the Uganda border. Contained within 77 days with no approved Sudan EBOV vaccine available.

Sudan ebolavirus outbreak — no approved vaccine or treatment available. Emergency vaccine trials launched mid-outbreak. 164 cases, 55 deaths.

Brief outbreak in North Kivu rapidly contained through ring vaccination. 6 cases and 5 deaths in 71 days.

14th Ebola outbreak in DRC. 6 cases and 4 deaths in Maniema Province, contained with ring vaccination.

Genomic sequencing revealed this outbreak was caused by a strain linked to 2018-2020 Kivu outbreak — likely a long-term survivor source ('flare-up').

DRC's 10th Ebola outbreak, occurring simultaneously with the tail of the 2018-2020 Kivu outbreak — an unprecedented dual-outbreak situation.

Largest DRC outbreak and second largest in history. 25 months in an active conflict zone. PHEIC declared July 2019. rVSV-ZEBOV and experimental treatments deployed.

First large-scale operational deployment of rVSV-ZEBOV ring vaccination. 3,000+ contacts vaccinated. Outbreak contained in 77 days.

First successful deployment of a prototype ring vaccination strategy with rVSV-ZEBOV under compassionate use. Contained in 42 days.

Ebola imported into Lagos via a Liberian-American diplomat arriving from the West Africa epidemic. Spread to Port Harcourt via a surviving patient. 20 cases and 8 deaths. Contained through aggressive contact tracing — WHO declared a model response.

Largest Ebola outbreak in history. PHEIC declared August 2014. Spread to 3 West African nations plus imported cases in Nigeria, Mali, USA, Spain, UK. Over 500 healthcare workers died.

7th DRC outbreak occurred simultaneously with the West Africa epidemic. 69 cases and 49 deaths. Contained independently by DRC, demonstrating improved national capacity.

Second outbreak caused by Bundibugyo ebolavirus in DRC's Orientale Province. 77 cases and 36 deaths confirmed over 80 days.

Sudan ebolavirus outbreak in Kibaale District with significant healthcare worker transmission. 24 cases and 17 deaths.

A single fatal Sudan ebolavirus case in Luwero District, Uganda. Rapid containment prevented secondary transmission.

Second Ebola outbreak in Kasai Occidental within 18 months. 32 cases and 15 deaths, raised concerns about ongoing endemicity in the region.

Discovery of the 5th ebolavirus species — Bundibugyo ebolavirus. 149 cases and 37 deaths. CFR of 25% was the lowest recorded for any ebolavirus species.

264 cases and 187 deaths in Kasai Occidental, DRC. Linked to consumption of bushmeat. Spread along major river arteries.

Sudan ebolavirus re-emerged in Yambio (now South Sudan) with 17 cases and 7 deaths. Rapid containment demonstrated improved response protocols.

The Republic of Congo Mbomo outbreak recorded the highest case fatality rate in Ebola history at 90% (143 cases, 128 deaths). Linked to gorilla die-offs in the region.

Cross-border outbreak on the Gabon/Congo border with 65 cases and 53 deaths, highlighting the need for regional coordination and shared wildlife surveillance.

Largest Sudan ebolavirus outbreak at the time. 425 cases and 224 deaths in Gulu, Masindi, and Mbarara districts. Spread primarily in hospitals and through funeral practices.

Uganda has suffered five Sudan ebolavirus outbreaks since 2000. Central African bat cave complexes are suspected reservoirs. Uganda has developed strong outbreak response capacity but lacks an approved Sudan EBOV vaccine — trials were launched during the 2022 outbreak.

Gabon's second 1996 outbreak in Booué. An infected physician was medically evacuated to Johannesburg, South Africa, where secondary infections occurred — the first Ebola case in South Africa.

An infected physician from the Gabon 1996 Booué outbreak was medically evacuated to Johannesburg — the southernmost confirmed Ebola case in history. A secondary infection occurred in a nursing staff member who survived. Highlighted the risk of medical evacuation without full PPE.

Outbreak traced to villagers who handled and ate a dead chimpanzee found in the forest near Mayibout. 31 cases and 21 deaths.

Landmark outbreak in Kikwit. Major amplification in Kikwit General Hospital. 315 cases and 254 deaths. Established modern barrier nursing and contact tracing protocols globally.

A Swiss ethologist who conducted a necropsy on a dead chimpanzee in Tai Forest developed EVD and survived. Tai Forest ebolavirus (the 4th species) was identified — the only known human case of this species.

First recognized Ebola outbreak in Gabon. Index cases were gold miners who came into contact with a dead chimpanzee. 52 cases and 31 deaths.

The equatorial forests spanning the Republic of Congo and Gabon have been the site of repeated Ebola spillovers linked to wildlife die-offs in gorillas, chimpanzees, and duikers. Fruit bats are the presumed reservoir host. Multiple outbreaks 1994–2005. Active forest surveillance is ongoing.

Sudan ebolavirus re-emerged in Nzara 3 years after the 1976 outbreak, confirming the virus persisted in the region's natural reservoir. 34 cases and 22 deaths.

A single fatal case of Zaire ebolavirus in a young girl in Tandala, DRC — the first confirmed Ebola recurrence after the 1976 Yambuku outbreak.

The first recognized outbreak of Sudan ebolavirus, occurring near-simultaneously with the Yambuku outbreak in DRC. 284 cases and 151 deaths. The virus was a distinct species from the DRC strain.

The first recognized outbreak of Ebola virus disease. Named after the Ebola River near the outbreak epicenter. 318 cases and 280 deaths (88% CFR). Transmitted largely via contaminated needles in Yambuku Mission Hospital.

DRC has experienced more Ebola outbreaks than any other country (17+). The Congo Basin equatorial forest harbors the likely reservoir host — fruit bats (Pteropodidae). Zaire ebolavirus spills over sporadically where human-wildlife contact is high. Ongoing wildlife surveillance by WHO and Africa CDC.